Pearl Review: Overview, Features, Pricing & Alternatives in 2025

Spotting missed dental problems is incredibly stressful.

If you’re evaluating dental AI, you probably want a way to catch more issues—and show patients you’re truly being thorough at every visit.

The reality is most dental imaging tools just aren’t sharp enough. You’re left second-guessing X-rays and losing precious chair time hunting for subtle problems that go undetected.

Here’s where Pearl stands out: it combines FDA-cleared AI image analysis with practice intelligence and automation tools. That means you get faster, more accurate diagnoses plus powerful workflow insights, all in one connected platform.

In this review, I’ll break down how Pearl can help you boost diagnostic accuracy and case acceptance without adding to your team’s stress.

We’ll cover everything you need to know in this Pearl review—from diagnostic features and real-world workflow tips to pricing and how it compares to top alternatives—to help you make a clear decision.

You’ll walk away knowing the features you need to catch issues earlier, streamline your practice, and make your next software choice with confidence.

Let’s dive right in.

Pearl Overview

Based in West Hollywood, Pearl is a dental AI specialist founded in 2016. I see their core mission as elevating patient care standards using practical, FDA-cleared artificial intelligence.

What truly sets them apart is a sharp focus on AI-powered clinical and practice insights. You’ll notice they serve dentists, large DSOs, and even labs, aiming to improve the entire practice workflow beyond just simple diagnostics.

Their recent $58 million funding round and pioneering FDA clearance for its AI platform signal serious market validation, which I’ll examine closely through this Pearl review.

Unlike competitors geared toward backend insurance review, Pearl emphasizes its real-time, patient-facing analysis. To me, it feels intentionally designed by dentists to improve chairside communication and directly boost case acceptance for your practice.

They work with a wide spectrum of users, from tech-forward solo practices and dental labs to the largest Dental Service Organizations and major insurance providers seeking consistency.

I found their entire business strategy is clearly aimed at connecting sophisticated AI diagnostics with tangible practice growth. They smartly link detected pathologies directly to your unscheduled treatment opportunities, which powerfully impacts your revenue streams.

Now let’s examine their core capabilities.

Pearl Features

Dreading manual dental diagnostics and paperwork?

Pearl features are truly transformative for dental practices, leveraging AI to enhance diagnostics and streamline operations. Here are the five main Pearl features that are making waves in dentistry.

1. Second Opinion® (AI-Powered Radiograph Analysis)

Worried about missing subtle diagnostic details?

Human oversight in interpreting dental X-rays can lead to missed conditions or delayed treatment, causing patient discomfort and higher costs.

Pearl’s Second Opinion acts as your AI co-pilot, meticulously scanning 2D radiographs to flag issues like caries or bone loss in real-time. From my testing, this FDA-cleared AI significantly enhances diagnostic precision, catching things the human eye might miss. This feature helps ensure more consistent and accurate diagnoses across your practice.

This means you can detect issues earlier, leading to less invasive treatments for patients and increased trust in your practice.

2. Practice Intelligence® (AI-Powered Clinical Performance)

Struggling to identify hidden revenue opportunities?

Without clear insights into patient data, you might miss out on unscheduled treatments or opportunities for more comprehensive care.

Practice Intelligence uses AI to analyze patient data, flagging diagnosed but unscheduled treatments and surfacing new opportunities. What I love about this approach is how it integrates seamlessly with your practice management system, giving you a complete view of clinical and operational performance. This feature helps optimize your production and patient care.

The result is your team can identify areas for growth and ensure patients receive the care they need, boosting your practice’s bottom line.

3. Smart Margin® (AI for Dental Labs)

Is manual margin marking slowing down your lab?

The traditional process of manually marking dental restoration margins is time-consuming and prone to errors, delaying turnaround times.

Smart Margin uses AI, trained by dental experts, to instantly and accurately mark these crucial margins on digital models. Here’s what I found: this feature drastically cuts down on lab design time, ensuring “super-human accuracy” and reducing costly reworks. This solution streamlines your entire restorative workflow.

This means dental labs can deliver restorations faster, with fewer errors, leading to happier dentists and more efficient production.

4. AI-Powered Insurance Verification

Tired of lengthy, complex insurance claims processing?

Slow and potentially fraudulent insurance claims can cost payers billions annually and create administrative headaches for providers.

Pearl’s AI solutions streamline the claims workflow by automatically identifying doctored or duplicate radiographic evidence. This is where Pearl shines: their patented AI, Pearl Protect, instantly validates claims, speeding up review and protecting against fraud. This feature significantly reduces processing time for insurance carriers.

So, as an insurer, you can process claims much faster, save billions in potential losses, and improve satisfaction for dental providers.

5. AI-Driven Interactive Schedule & Patient Recall

Is your front office overwhelmed with scheduling and recalls?

Inefficient scheduling and generic recall methods can lead to empty chairs and missed patient appointments, hurting daily production.

Pearl’s AI optimizes your daily schedule, anticipating patient needs and maximizing chair time, making morning huddles more productive. The intelligent recall and marketing lists leverage AI insights for targeted outreach, identifying unmet treatment opportunities. This feature helps keep your practice diary full.

This means your front office staff can focus on patient care rather than administrative juggling, leading to increased daily production and patient retention.

You’ll actually appreciate how these Pearl features work together as an integrated, AI-powered platform rather than separate tools. The cohesive design genuinely enhances every aspect of your dental practice.

Pearl Pricing

How transparent is their pricing?

Pearl pricing for their dental AI solutions offers a mix of transparent subscription fees for specific products and custom quotes for broader enterprise needs, helping you understand your investment.

1. Pricing Model & Cost Factors

Understanding Pearl’s cost structure.

Pearl’s pricing model combines fixed monthly subscriptions for core products like Second Opinion and Practice Intelligence with custom quotes for specialized solutions like Smart Margin. Your costs primarily depend on the specific module you choose and your operational scale, such as the number of offices utilizing Practice Intelligence.

From my cost analysis, this means your budget gets clear line items for key AI tools, with flexibility for larger deployments.

2. Value Assessment & ROI

Is Pearl worth the investment?

Pearl’s AI solutions aim to boost diagnostic accuracy and operational efficiency, directly impacting your practice’s bottom line. The ability to detect more lesions (36% more with Second Opinion) means you uncover hidden treatment opportunities and increase production, leading to tangible ROI that justifies the monthly fees.

What I found regarding pricing is that this translates to increased revenue and improved patient care, ultimately benefiting your practice’s profitability.

3. Budget Planning & Implementation

Consider total cost of ownership.

Beyond the monthly subscriptions, remember the one-time setup fees for Second Opinion and historical AI analysis for Practice Intelligence. While Pearl assists with installation and integration, factor these initial costs into your budget planning. They offer no lock-in contracts, which reduces your long-term commitment risk.

Budget-wise, you can expect predictable monthly costs after initial setup, with robust support included to maximize your investment.

My Take: Pearl’s pricing reflects a strategic balance between transparent per-product subscriptions and custom enterprise solutions, making it suitable for practices of all sizes seeking advanced dental AI.

The overall Pearl pricing reflects measurable value for your dental practice operations.

Pearl Reviews

What do Pearl reviews reveal?

I analyzed numerous Pearl reviews to understand what actual users think about the software. This section covers their experiences, common praise, and frequent complaints.

1. Overall User Satisfaction

Users seem largely impressed.

From my review analysis, Pearl generally earns high marks for its diagnostic capabilities and patient communication tools. What I found in user feedback is that users find Pearl to be an “incredibly clever” solution, often integrating smoothly into existing workflows.

This suggests you can expect a significant uplift in diagnostic accuracy and patient engagement.

2. Common Praise Points

The AI’s diagnostic power shines.

Users consistently praise Pearl’s AI for enhancing diagnostic precision and improving patient understanding. Review-wise, the “Second Opinion” platform is a consistent highlight, making it easier to spot subtle issues and communicate findings clearly to patients.

This means you can anticipate earlier disease detection and increased treatment acceptance from patients.

3. Frequent Complaints

Cost and manual upload limitations surface.

While largely positive, some Pearl reviews highlight the software’s cost as a barrier, and the inability to manually upload radiographs into Second Opinion. What stands out in customer feedback is how the lack of manual upload can disrupt certain specific workflows, especially for practices reliant on diverse imaging sources.

These concerns are notable, but generally minor compared to the core benefits Pearl provides.

The overall Pearl reviews paint a picture of highly satisfied users, with minor points of friction for specific use cases.

Best Pearl Alternatives

Choosing the best AI dental solution?

The best Pearl alternatives include several strong options, each better suited for different dental practice needs, specific diagnostic requirements, and operational workflows.

1. Overjet

Need precise, quantified bone loss measurements?

Overjet excels if your practice critically requires FDA-cleared, millimeter-accurate bone loss quantification, or if you prefer a tool with a strong history of working with insurance providers. From my competitive analysis, Overjet offers unique quantified bone level analysis, though its UI might feel more corporate than Pearl’s.

Choose Overjet when precise bone loss quantification is paramount for your diagnostic and treatment planning.

2. Denti.AI

Does your workflow require manual X-ray uploads?

Denti.AI is a better choice if your current workflow requires the flexibility to manually import radiographs into the AI analysis software. Alternative-wise, Denti.AI supports diverse manual import needs, a feature Pearl’s Second Opinion currently lacks for some workflows.

Consider Denti.AI when manual X-ray import flexibility is a key operational requirement for your practice.

3. Diagnocat

Are 3D CBCT images central to your diagnoses?

Diagnocat is currently the only AI solution that reads 3D cone beam computed tomography (CBCT) images, offering a significant advantage for practices utilizing 3D imaging. What I found comparing options is that Diagnocat uniquely analyzes 3D dental CBCT images, which Pearl does not currently offer with Second Opinion.

For your specific situation, choose Diagnocat if 3D CBCT image analysis is a primary need in your diagnostic process.

4. CareStack

Seeking an all-in-one practice management system?

CareStack provides a comprehensive, cloud-based dental practice management system (PMS) with integrated AI capabilities, handling scheduling, billing, and patient records. From my analysis, CareStack is a full practice management solution, making Pearl a complementary diagnostic tool within a larger ecosystem.

You’ll want to consider CareStack when your priority is an integrated PMS over Pearl’s specialized AI diagnostics.

Ultimately, the best Pearl alternatives depend on your specific clinical needs and practice integration priorities, not just AI features.

Pearl Setup

What does Pearl implementation really involve?

This Pearl review section breaks down the practical realities of deploying this AI solution, helping you understand the Pearl setup process and what it takes to get up and running effectively.

1. Setup Complexity & Timeline

Is Pearl’s setup truly “hands-off simple”?

Pearl setup involves integrating its cloud-based AI with your existing dental imaging and practice management systems. While it aims for simplicity, the timeline depends on your current tech ecosystem’s seamlessness. What I found about deployment is that Pearl-assisted setup speeds things up, but complex existing setups will require more attention.

You’ll want to assess your current technology’s readiness for integration to set realistic expectations for your go-live.

2. Technical Requirements & Integration

How will Pearl fit into your existing IT?

As a cloud solution, Pearl primarily requires network connectivity for image syncing and compatibility with your current imaging software. From my implementation analysis, **Pearl integrates with the most imaging and PMS software on the market, which simplifies adoption for many practices.

Plan for your IT team to verify system compatibility and ensure robust network requirements are met for smooth data flow.

3. Training & Change Management

Will your team embrace this new AI?

Pearl aims for intuitive designs, but team training is still crucial for full proficiency, especially with Second Opinion. From my analysis, staff proficiency ensures you maximize Pearl’s diagnostic and communication benefits, avoiding underutilization or workflow hiccups after deployment.

Invest in dedicated training time and clearly communicate the benefits to your team to drive enthusiasm and overcome initial learning curves.

4. Support & Success Factors

How much support will Pearl offer?

Pearl includes dedicated customer support with its Practice Intelligence plan, indicating a commitment to helping you succeed. What I found about deployment is that responsive vendor support can significantly smooth your implementation journey, especially when unexpected questions arise.

You’ll want to leverage their support, provide feedback, and actively integrate Pearl into daily workflows for continuous improvement and maximum impact.

Overall, the Pearl setup process emphasizes cloud-based simplicity and vendor support, making it manageable for practices ready to integrate AI into their workflow.

Bottom Line

Should you invest in this dental AI solution?

My Pearl review shows a powerful AI platform for dental practices aiming to enhance diagnostics, improve patient education, and optimize operations.

1. Who This Works Best For

Dental professionals aiming to elevate patient care.

Pearl excels for single dental practices and multi-site DSOs seeking AI-driven insights for real-time X-ray analysis, improved diagnostics, and enhanced patient communication. What I found about target users is that your success hinges on integrating AI to consistently identify issues and boost treatment acceptance.

You’ll particularly benefit if you prioritize diagnostic accuracy and want a visually engaging tool to explain findings to patients.

2. Overall Strengths

Unmatched AI accuracy and patient communication tools.

The software delivers highly accurate, FDA-cleared AI for X-ray analysis, empowering dentists with a “second opinion” that aids in earlier disease detection and strengthens patient understanding. From my comprehensive analysis, its seamless integration with existing X-ray software makes adoption straightforward for your team.

These strengths translate into improved clinical outcomes, increased case acceptance, and more efficient practice workflows for your business.

3. Key Limitations

Pricing transparency and specific workflow constraints.

One notable drawback is the lack of publicly available comprehensive pricing, requiring direct contact to understand costs for your practice. Based on this review, the inability to manually upload radiographs into Second Opinion might also be a concern for some workflows.

I find these limitations manageable if you prioritize cutting-edge AI over immediate cost transparency or specific manual import capabilities.

4. Final Recommendation

Pearl earns a strong recommendation for dental innovation.

You should choose this software if your practice is ready to embrace AI for advanced diagnostics, better patient engagement, and operational efficiency improvements. From my analysis, this solution is ideal for proactive, growth-oriented dental practices seeking a competitive edge through technology adoption.

My confidence level is high for practices aiming to upgrade their diagnostic capabilities and foster greater patient trust.

This Pearl review reveals strong value for the right dental practice, offering cutting-edge AI to elevate patient care and practice performance.