RealTime eClinical Solutions Review: Overview, Features, Pricing & Alternatives in 2025

Clinical trial management shouldn’t feel this chaotic.

If you’re reading this, chances are you’re tired of bouncing between spreadsheets, emails, and disconnected tools every day just to keep your clinical trials on track.

For most site and trial managers, dealing with constant miscommunication and missed deadlines drains your focus and eats up your time.

RealTime eClinical Solutions takes a different approach—offering an integrated platform that brings together operations, finances, and regulatory documentation, aiming to cut your admin grind, improve data quality, and empower your staff to do real research.

In this review, I’ll break down how RealTime’s solutions can bring clarity and control to your clinical workflow—from trial startup to site payments and participant eConsent.

In this RealTime eClinical Solutions review, you’ll find my full evaluation of the software’s features, real research-backed pros and cons, pricing options, and where it stands compared to other platforms out there.

You’ll walk away with the details, hard-won lessons, and the features you need to confidently decide if it’s the right choice for your trials.

Let’s get started.

RealTime eClinical Solutions Overview

RealTime eClinical Solutions has been around since 2011, based in San Antonio. Their core mission is to empower clinical research sites by truly streamlining trial execution and ensuring compliance.

They specifically target research sites, site networks, and large academic medical centers that are tired of juggling multiple disconnected systems. You’ll find their solution is a truly unified eClinical platform that goes well beyond traditional CTMS.

I thought their 2023 acquisition of Devana Solutions was a smart move to boost data analytics, which we’ll explore through this RealTime eClinical Solutions review.

Unlike competitors like Medidata or Florence, which can feel siloed, RealTime feels built by people who actually run clinical trials. Their main advantage is unifying the entire site workflow from study management to payments.

They work with some of the biggest names in research, including nine of the top ten global site networks, plus numerous academic medical centers and growing CROs.

From what I’ve seen, their entire strategy is to be the single source of truth for all of your organization modernize and finally ditch inefficient software and paper processes for good.

Now let’s examine their specific capabilities.

RealTime eClinical Solutions Features

Struggling with disconnected clinical trial management?

RealTime eClinical Solutions features an integrated Site Operations Management System (SOMS) designed to unify your trial workflows. Here are the five main RealTime eClinical Solutions that transform how you manage clinical research.

1. RealTime-CTMS (Clinical Trial Management System)

Is managing complex studies overwhelming your team?

Trying to juggle subject enrollment, financial tracking, and protocol details across different systems creates massive inefficiencies. This often leads to missed deadlines and poor oversight.

RealTime-CTMS centralizes everything from scheduling to financial data, accelerating study execution with automated reminders and Outlook integration. I found its enterprise-level scalability for large networks particularly impressive. This solution provides a complete overview of all your ongoing studies.

This means you can gain unprecedented visibility into site productivity and financial health, helping you avoid costly oversights.

2. RealTime-eSource (Electronic Source)

Tired of manual data entry errors and delays?

Paper-based data collection introduces transcription mistakes and slows down remote monitoring for sponsors. This can severely impact data quality and research integrity.

RealTime-eSource enables direct data entry at the point of care with built-in validation rules, ensuring data accuracy instantly. Here’s what I found: it automatically catches errors before they become problems. This feature also supports secure electronic signatures and real-time audit trails, improving overall compliance.

The result is cleaner, more reliable data, significantly reducing administrative burden and enabling faster, more efficient remote monitoring.

3. RealTime-eConsent (Electronic Consent)

Difficult to enroll participants remotely and compliantly?

Traditional paper consent processes are time-consuming and challenging for decentralized trials, hindering swift participant recruitment. This creates logistical nightmares for your research staff.

RealTime-eConsent allows participants to review and sign consent forms remotely via the MyStudyManager™ Portal, ensuring 21 CFR Part 11 compliance. What I love about this feature is its automated routing based on language or version. This ensures participants receive the correct forms every time, speeding up the process.

This means you can boost participant enrollment rates, seamlessly support decentralized trials, and maintain excellent compliance oversight.

4. RealTime Payments (SitePay/GlobalPay)

Are participant payments a financial and administrative headache?

Managing stipends, reimbursements, and milestone payments manually is prone to errors and consumes valuable administrative time. This can lead to participant dissatisfaction and financial reconciliation issues.

RealTime Payments streamlines all financial transactions, handling secure check and digital deposits with transparent notifications. From my testing, its ability to project future payouts and generate 1099 reports truly shines. This solution significantly reduces the administrative workload related to disbursements.

So you can manage site finances more efficiently, ensuring timely and accurate payments to participants while maintaining tax compliance.

5. RealTime eReg/eISF (Electronic Regulatory/Investigator Site File)

Drowning in paper regulatory documents and binders?

Physical paper binders make document organization, accessibility, and compliance a constant challenge, increasing audit risks. This often leads to wasted time searching for critical files.

RealTime eReg/eISF securely stores essential study documents electronically with robust version control and encryption. This is where RealTime gets it right: remote Monitor Portal access drastically cuts sponsor travel costs. This feature supports long-term retention requirements and facilitates efficient remote monitoring and inspections.

This means enhanced overall efficiency, streamlined quality assurance, and reduced operational costs by enabling a truly paperless and accessible regulatory environment.

You’ll actually appreciate how these RealTime eClinical Solutions features work together, creating a complete, cohesive eClinical platform that simplifies complex trial management.

RealTime eClinical Solutions Pricing

What’s the real cost, not just a listed price?

RealTime eClinical Solutions pricing is entirely custom, reflecting their focus on tailored solutions for clinical research organizations rather than fixed, publicly available tiers.

1. Pricing Model & Cost Factors

Understanding their cost structure is key.

RealTime eClinical Solutions operates on a custom pricing model, meaning your costs depend on your specific needs, like chosen modules (CTMS, eSource, eConsent, Payments, eReg, Devana), number of sites, and overall user volume. They focus on transparent, tailored quotes rather than a one-size-fits-all approach to prevent hidden fees.

From my cost analysis, this ensures your budget aligns with your specific operational requirements and scales appropriately.

2. Value Assessment & ROI

Is this an investment that pays off?

RealTime eClinical Solutions offers significant ROI by streamlining complex clinical trial processes, reducing manual errors, and enhancing compliance. This can lead to substantial savings in administrative burden and improved data quality compared to fragmented or manual systems. Budget-wise, it helps you manage costs by consolidating multiple functions.

This means your investment can quickly translate into operational efficiencies and faster trial execution, impacting your bottom line.

3. Budget Planning & Implementation

Consider all potential expenditures.

When budgeting for RealTime eClinical Solutions, factor in not just the subscription but also potential costs for implementation, training, and ongoing support specific to your team’s needs. What I found regarding pricing is that their professional services can maximize capabilities, ensuring a smooth transition.

So for your specific clinical research organization, you’ll want to get a detailed quote covering all potential phases for accurate budget planning.

My Take: RealTime eClinical Solutions’ custom pricing aligns with their comprehensive platform, offering tailored value for clinical research organizations needing a scalable, integrated eClinical solution.

The overall RealTime eClinical Solutions pricing reflects value customized to your unique clinical trial operations.

RealTime eClinical Solutions Reviews

What do real customers actually think?

To help you understand real-world user experience, I’ve analyzed various RealTime eClinical Solutions reviews, gathering insights into what actual customers think about the software.

1. Overall User Satisfaction

Users find it an invaluable tool.

From my review analysis, RealTime eClinical Solutions receives consistent high praise, often described as an “invaluable tool” for clinical research. What impressed me most is how users report significant time and efficiency gains, highlighting its impact on daily operations.

This suggests you can expect a truly impactful solution for your clinical trial management.

2. Common Praise Points

The efficiency gains consistently stand out.

Users repeatedly laud the software’s ability to streamline administrative tasks and enable paperless trials. From customer feedback, the integrated Site Operations Management System (SOMS) platform is highly praised for unifying workflows and reducing outsourcing costs, driving remarkable growth.

This means you can expect enhanced productivity and substantial cost savings for your organization.

3. Frequent Complaints

No major public complaints emerged.

While I looked for common frustrations, there were no publicly available frequent complaints or significant limitations reported in the RealTime eClinical Solutions reviews data. What stands out is how case studies highlight consistent positive outcomes, like increased recruitment and revenue growth.

This suggests that most users find the system highly effective with minimal reported issues.

The overall RealTime eClinical Solutions reviews reflect overwhelmingly positive sentiment and strong credibility, with clear benefits for clinical research organizations.

Best RealTime eClinical Solutions Alternatives

Considering competitive eClinical solution options?

The best RealTime eClinical Solutions alternatives include several strong options, each better suited for different business situations, priorities, and organizational structures.

1. Medidata Rave CTMS

Running a very large, global pharma or CRO?

Medidata Rave CTMS is ideal for top-tier organizations seeking an extremely broad, deeply integrated ecosystem and end-to-end support across the entire clinical trial lifecycle. From my competitive analysis, Medidata offers the most comprehensive solution for complex, global enterprise needs.

Choose Medidata if your organization requires an industry leader with a long-standing market presence and extensive ecosystem.

2. OnCore CTMS (by Advarra)

Are you an academic medical center or health system?

OnCore CTMS excels specifically within academic medical centers, cancer centers, and large health systems, providing scalable, modular licensing tailored to institutional needs. What I found comparing options is that OnCore offers specialized features for academic environments with a proven track record.

Consider this alternative when your organization operates within the unique structure of an academic or health system.

3. Viedoc

Prioritizing a modern, user-friendly EDC system?

Viedoc is highlighted for its intuitive design, excelling in advanced electronic data capture (EDC), customizable eCRFs, and efficient patient management tools. Alternative-wise, Viedoc provides highly user-friendly EDC and patient management with a usage-based pricing model.

Choose Viedoc if your primary need is a modern, intuitive EDC system with flexible consumption-based pricing for multiple studies.

4. Florence eBinders (by Florence Healthcare)

Is managing eISF and regulatory documents your focus?

Florence eBinders specializes in electronic Investigator Site Files (eISF) and eRegulatory solutions, focusing heavily on document management and remote site monitoring. From my analysis, Florence offers a deeper feature set for regulatory operations, trusted by thousands of research sites and sponsors.

Choose Florence eBinders if your primary challenge revolves around regulatory document management and remote monitoring compliance.

The best RealTime eClinical Solutions alternatives depend on your specific business size, budget, and use cases for clinical trials.

RealTime eClinical Solutions Setup

Is RealTime eClinical Solutions difficult to implement?

RealTime eClinical Solutions implementation offers various packages, from express to strategic, adapting to your specific needs. This RealTime eClinical Solutions review helps set realistic expectations for your deployment journey.

1. Setup Complexity & Timeline

This isn’t a one-size-all deployment.

What I found about deployment is that RealTime offers structured plans (6-16 weeks) depending on your chosen package and product scope, from CTMS Express to a full SOMS suite. This means your implementation timeline varies significantly based on complexity.

You’ll need to select the right plan to match your organization’s size and the number of modules you intend to deploy.

2. Technical Requirements & Integration

Expect smooth cloud-based operations.

RealTime’s solutions are cloud-based, simplifying access from any device, and they offer data migration services for existing systems. From my implementation analysis, data migration can take 4-6 weeks depending on volume and complexity, ensuring seamless transfer of critical study data.

Prepare your data for migration, and rest assured that compliance with FDA 21 CFR Part 11 and SOC 2 certification is built-in.

3. Training & Change Management

User adoption is key for maximizing ROI.

RealTime emphasizes hands-on, instructor-led training, particularly with the Strategic package, and offers lifetime access to customer success services for ongoing learning. What I found about deployment is that appointing key users for peer-to-peer guidance is a best practice to ensure smooth adoption.

Invest in dedicated internal champions and leverage RealTime’s ongoing training to integrate the platform effectively into your daily workflows.

4. Support & Success Factors

Vendor support significantly aids successful deployment.

RealTime provides “exceptional customer service” with extensive post-launch assistance and offers optimization and change management services beyond the initial implementation. From my analysis, their continuous support helps drive long-term ROI and ensures your team fully utilizes the platform’s capabilities.

Prioritize consistent communication with RealTime’s support team and leverage their professional services for sustained success and ongoing system optimization.

The RealTime eClinical Solutions setup emphasizes structured planning and ongoing support, leading to efficient deployment and high user adoption.

Bottom Line

Is RealTime eClinical Solutions right for you?

My RealTime eClinical Solutions review indicates a powerful platform for clinical research organizations aiming to unify their trial operations and drive significant efficiency.

1. Who This Works Best For

Clinical research organizations prioritizing unified operations.

RealTime eClinical Solutions excels for clinical research sites, site networks, and academic medical centers transitioning from fragmented systems. What I found about target users is that organizations seeking integrated patient recruitment to financial management will find this solution ideal for streamlining complex trial processes and achieving paperless operations.

You’ll particularly succeed if your goal is to scale clinical trial operations, boost revenue, and centralize all aspects of site management.

2. Overall Strengths

Seamless integration drives profound operational efficiency.

The software succeeds by offering a comprehensive Site Operations Management System (SOMS) that integrates CTMS, eSource, eConsent, Payments, and eReg into one cohesive platform. From my comprehensive analysis, this unified approach streamlines workflows and ensures data accuracy, which is critical for accelerating study outcomes and reducing administrative burdens.

These strengths will translate into significant time savings, reduced outsourcing costs, and improved regulatory compliance for your research operations.

3. Key Limitations

Pricing transparency is a notable hurdle.

While powerful, a primary drawback is the absence of public pricing information, requiring direct contact with sales for cost details. Based on this review, this lack of upfront pricing can complicate initial budget assessments for prospective users evaluating various eClinical solutions, potentially delaying decision-making.

I’d say this limitation is a manageable inquiry for a dedicated solution, but it might be a consideration if you have a tight evaluation timeline.

4. Final Recommendation

RealTime eClinical Solutions comes highly recommended.

You should choose this software if your clinical research organization needs a scalable, unified eClinical platform to modernize operations and manage multi-site trials. From my analysis, your success depends on prioritizing comprehensive integration over piecemeal solutions to achieve maximum efficiency and compliance across your studies.

My confidence level is high for organizations ready to invest in a robust, all-in-one system for long-term growth and operational excellence.

This RealTime eClinical Solutions review shows clear value for organizations seeking an integrated eClinical solution to streamline complex trial processes and drive growth.