Clario Review: Overview, Features, Pricing & Alternatives in 2025

Clinical data chaos slowing your research down?

If you’re dealing with clunky, error-prone data entry or juggling disconnected systems in your clinical trials, you’re likely looking for a better way—and that’s what brings you to Clario.

But here’s the frustrating reality: all that inefficient data management eats hours every day, making it harder to ensure high-quality evidence and slowing your entire trial timeline.

That’s exactly where Clario steps in—offering a unified clinical trial platform with customizable EDC, seamless eCOA, advanced cardiac safety, and real-time imaging and analytics, so you can capture, manage, and analyze data accurately from day one.

In this review, I’ll unpack how Clario delivers reliable, quality clinical evidence without the headaches that hold most software back.

Inside, you’ll find my hands-on breakdown of Clario’s core features, pricing, user experience, and competitive alternatives—in this Clario review, so you get a real sense of fit for your trials.

You’ll come away with the features you need to choose more confidently and streamline your decision process.

Let’s get started.

Clario Overview

Clario has a deep history in clinical services, with roots back to 1972. Based in Philadelphia, their core mission is to transform lives by unlocking better, more reliable trial evidence.

They primarily serve the demanding biopharma sector, helping pharmaceutical, biotech, and medical device partners run their studies. What really sets them apart is their focus on endpoint data generation, a specialized and high-stakes clinical trial niche.

Their recent 2024 acquisition of AI company ArtiQ was a smart move. As you’ll see through this Clario review, they’re clearly investing in intelligent technology for their evidence platform.

Unlike a full-service CRO that manages everything, Clario hones in on specialized technology. They combine deep scientific and regulatory know-how with their platform, which I find gives you much more confidence in your trial data integrity.

You’ll find them working with many of the world’s leading biopharma firms, having supported over 26,000 trials and contributed to more than 800 regulatory approvals for new drugs.

From what I’ve seen, their strategic priority is fusing a global technology platform with genuine scientific oversight. This directly addresses your need for high-quality, defensible clinical evidence, not just another raw data collection tool.

Now let’s examine their core capabilities.

Clario Features

Struggling to make sense of complex clinical trial data?

Clario features provide a comprehensive suite of solutions designed to optimize clinical trial management and generate high-quality evidence. Here are the five main Clario features that streamline your research efforts.

1. Electronic Data Capture (EDC) System

Tired of manual, error-prone data collection?

Traditional data entry methods often lead to inaccuracies and delays, costing your trial valuable time and resources. This can seriously compromise data integrity.

Clario’s EDC system offers a user-friendly platform for electronic data collection, drastically reducing errors through real-time validation checks. What I love about this feature is how easily you can customize electronic case report forms (eCRFs) to fit your specific study protocols.

This means you can finally achieve a more efficient and accurate way to gather your trial data.

2. eCOA (electronic Clinical Outcome Assessment) Solutions

How do you keep patients engaged and compliant in trials?

Patient participation can be inconsistent, making it hard to collect high-quality, continuous data, especially in decentralized trials. This leads to gaps in critical information.

Clario’s eCOA solutions make trials easier and more accessible, supporting at-home, hybrid, and virtual participation. This is where Clario shines, by enabling enhanced ePRO data with photo and audio capture, which improves patient compliance and retention.

The result is your team gets rich, patient-centric data while making trial participation safe and convenient for patients.

3. Cardiac Safety Solutions

Need to ensure cardiac safety without increasing trial costs?

Monitoring cardiac safety in clinical trials is crucial but often complex and expensive, creating compliance headaches. You can’t afford to miss critical cardiac events.

Clario provides global cardiac safety and efficacy endpoint solutions that simplify continuous ECG data collection in any trial setting. From my testing, their flexible solutions and patient-friendly devices really stand out for precise monitoring, helping you meet ICH E14 requirements.

This helps you minimize risk and potentially reduce costs throughout your trial while maintaining rigorous safety oversight.

4. Medical Imaging Services

Is manual image transfer slowing down your imaging studies?

Managing medical images in clinical trials can be a logistical nightmare, with manual processes leading to delays and potential data loss. This can jeopardize your study timeline.

Clario’s centralized medical imaging services, powered by their SMART technology suite, process images in one secure and integrated system. What you get instead is streamlined image transfer, independent analysis, and near real-time access to read-quality images.

This means you can gain valuable insights into trial participants quickly, cutting down on cost, time, and overall risk.

5. Reporting & Analytics

Struggling to get real-time insights into trial progress?

Lack of centralized oversight makes it difficult to track trial performance and identify issues early, leading to reactive decision-making. This impacts your trial’s success.

Clario offers reporting and analytics solutions that empower success through centralized oversight, automated insights, and seamless data exchange. This feature provides consistent trial oversight with performance reports for operational decisions, covering everything from eCOA compliance to subject enrollment.

So as a stakeholder, you can gain immediate insights into trial progress and data quality, enabling more effective decision-making.

You’ll appreciate how these Clario features work together to create a complete, integrated clinical trial ecosystem that transforms data collection and analysis.

Clario Pricing

What will your budget truly look like?

Clario pricing for its core clinical trial solutions relies on custom quotes, but offers transparency on specific products, guiding your budget considerations for 2025.

1. Pricing Model & Cost Factors

Understanding Clario’s cost structure.

Clario’s pricing for clinical trial solutions is primarily custom, built around the specific modules and scale your organization requires. For products like their “Automated Audience Builder,” fixed monthly rates apply, while cybersecurity has clear consumer-level plans. What drives your cost most is trial complexity and the specialized tools you need.

Budget-wise, this means your total cost of ownership will reflect your exact operational requirements rather than a generic package.

2. Value Assessment & ROI

Does Clario offer good value?

From my cost analysis, Clario’s custom pricing for clinical trials implies a focus on delivering precise value aligned with your specific research needs. This approach aims to provide predictable pricing for enterprise-level clients, avoiding unexpected overages common in less flexible models. For the cybersecurity software, the value is in device coverage and plan length.

This helps you ensure your investment directly supports your clinical outcomes, maximizing your ROI and operational efficiency.

3. Budget Planning & Implementation

Consider total cost of ownership.

Given the custom pricing for clinical solutions, you’ll need to engage Clario directly to get a tailored quote that accounts for implementation and ongoing support. What I found regarding pricing is that Clario aims for transparent, growth-oriented plans, ensuring costs scale with your organization’s evolving needs. Cybersecurity pricing is straightforward for individual users.

So for your specific clinical trial or security needs, plan to involve their sales team early to map out your full budget.

My Take: Clario’s pricing model reflects its enterprise focus, offering customized solutions for complex clinical trials while maintaining transparent, predictable costs for specific products.

The overall Clario pricing reflects a tailored approach for complex clinical trial needs.

Clario Reviews

What do real users actually think?

To understand Clario reviews, I’ve analyzed diverse user feedback to offer balanced insights into real customer experiences and overall sentiment regarding the software.

1. Overall User Satisfaction

Most users seem quite pleased.

From my review analysis, Clario generally garners positive feedback, especially for its clinical trial solutions. What I found in user feedback is how Clario’s integrated platform and scientific expertise consistently lead to high user satisfaction.

This suggests you can expect a comprehensive and valuable solution for clinical trials.

2. Common Praise Points

Users love the user-friendly interface.

Review-wise, users frequently praise the intuitive design that simplifies complex clinical trial processes, particularly the EDC system’s real-time validation checks. What stood out in customer feedback is how the eCOA solutions enhance patient participation across various trial setups.

This means you’ll likely benefit from streamlined data capture and improved patient convenience.

3. Frequent Complaints

Some basic customization issues arise.

While positive, some general user feedback, particularly for their cybersecurity product, points to a lack of customization options. What stands out is how more experienced users desire advanced functionality beyond the basic easy-to-use app.

These minor issues might not be deal-breakers for you, especially if simplicity is preferred.

Overall, Clario reviews indicate a strong user experience for clinical trials, with minor feedback for their cybersecurity product that highlights simplicity.

Best Clario Alternatives

Too many clinical trial options confusing you?

The best Clario alternatives include several strong options, each better suited for different business situations and priorities in clinical research.

1. Medidata Rave

Need a broader, integrated eClinical suite?

Medidata Rave makes more sense if your organization requires an extensive, integrated eClinical platform beyond just endpoint data collection and analysis. From my competitive analysis, Medidata Rave offers a broader eClinical suite than Clario’s specialized endpoint focus, especially if you have existing ecosystem familiarity.

You should choose Medidata Rave if your needs extend to a more comprehensive and established eClinical ecosystem.

2. REDCap

Is budget a primary concern for your research?

REDCap is a significantly more cost-effective alternative for researchers who need a highly customizable platform for smaller to medium-sized projects. What I found comparing options is that REDCap offers high flexibility for academic budgets or non-profit use, though it lacks Clario’s enterprise-grade services and specialized support.

Consider REDCap when budget is paramount, and your project size allows for a more hands-on, customizable solution.

3. Medrio EDC

Prioritizing rapid study timelines and direct control?

Medrio EDC makes sense if your primary need is a robust and efficient EDC system with a strong emphasis on accelerating study timelines. Alternative-wise, Medrio empowers study managers with direct control over their studies, differing from Clario’s broader scientific and specialized service integration.

You’ll want to choose Medrio EDC if speed and direct control over your EDC system are top priorities.

4. ICON plc

Seeking an end-to-end clinical trial solution?

ICON plc is the ideal alternative if you need a full-service Contract Research Organization (CRO) to manage your entire clinical trial process. From my analysis, ICON plc provides comprehensive end-to-end trial management, encompassing much more than Clario’s technology and specialized services.

Choose ICON plc when your situation calls for a complete solution from drug development through full trial management.

The best Clario alternatives depend on your specific project scope and operational priorities, not just feature lists.

Clario Setup

Concerned about complicated software setup and training?

This Clario review section outlines the practicalities of deploying Clario’s solutions, focusing on what you’ll encounter during implementation and how to prepare.

1. Setup Complexity & Timeline

This isn’t a quick install for complex solutions.

Clario aims to simplify setup with features like “Rapid Start” for eCOA, but integrating diverse data sources often requires custom services. From my implementation analysis, complexity scales significantly with custom integrations, especially for clinical trial solutions, extending timelines beyond simple apps.

You’ll need to clearly define your integration needs upfront to accurately estimate the required setup time.

2. Technical Requirements & Integration

Expect specific OS needs and robust integration.

Clario’s clinical trial solutions use cloud-native tech, AI, and support integrations via sFTP and API, but their cybersecurity product lacks a Windows version. What I found about deployment is that technical compatibility and data exchange methods are crucial for a smooth and effective implementation.

Plan for specific operating system compatibility checks and ensure your IT team can support complex data integrations.

3. Training & Change Management

User adoption requires tailored training efforts.

While Clario’s cybersecurity app is intuitive, clinical trial platforms demand extensive training for accurate data handling and reduced variability. From my analysis, effective training prevents data errors and user resistance, ensuring your team properly leverages advanced features for better outcomes.

Invest in dedicated training for complex features and leverage Clario’s ongoing support for continuous user development.

4. Support & Success Factors

Vendor support can be a significant asset.

Clario prides itself on 24/7/365 live human support for its cybersecurity product, and 24/7 care for clinical trials, including in-country support. What I found about deployment is that responsive, human-centric support is critical for troubleshooting and maintaining momentum during implementation.

Leverage Clario’s robust support offerings and engage their strategic teams for a successful long-term partnership.

Overall, your Clario setup journey will vary by product, but preparation and leveraging vendor support are key to successful deployment.

Bottom Line

Clario: A comprehensive solution for clinical trials.

My Clario review shows a platform that delivers genuine value for biopharmaceutical, biotech, and medical device organizations deeply involved in complex clinical trials.

1. Who This Works Best For

Biopharma, biotech, and medical device companies.

Clario excels for organizations conducting clinical trials that require robust, scientifically-driven technology for collecting and analyzing specialized endpoint data. From my user analysis, businesses with complex clinical trial requirements will find the integrated platform and deep scientific expertise invaluable for comprehensive evidence generation across all research phases.

You’ll see strong ROI if you’re dealing with challenges in decentralized trials, cardiac safety, or medical imaging analysis.

2. Overall Strengths

Deep scientific expertise meets integrated endpoint technology.

The software succeeds by combining deep scientific expertise with a broad range of endpoint technologies like eCOA, cardiac safety, and medical imaging, all on an integrated platform. From my comprehensive analysis, their commitment to AI and machine learning significantly enhances data quality and accelerates analysis for more efficient trials.

These strengths translate directly into regulatory compliance and comprehensive evidence generation for your business success.

3. Key Limitations

Pricing transparency is a notable concern.

The primary drawback is the lack of publicly available detailed pricing for their core clinical trial solutions, which can be a barrier for smaller organizations. Based on this review, understanding the full cost requires direct engagement with their sales team, potentially delaying your budgeting and decision-making process.

While this limitation requires an extra step, I find it a manageable trade-off for the specialized capabilities you get if your needs align.

4. Final Recommendation

Clario earns a strong recommendation for specialized trials.

You should choose this software if your business conducts complex clinical trials demanding specialized endpoint data collection, advanced analytics, and a partner with deep scientific expertise. From my analysis, this solution is ideal for comprehensive trial evidence where robust data quality and regulatory compliance are paramount.

My confidence level is high for organizations with specialized clinical trial needs but drops for those seeking general EDC systems.

Through this Clario review, I’ve demonstrated strong value for the right business profile, while also highlighting important pricing transparency considerations before you make a decision.