Sidexis 4 vs SimplePractice Comparison: Reviews, Features, Pricing & Alternatives in 2026

Detailed side-by-side comparison to help you choose the right solution for your team

Updated Apr 2026 8 min read

Sidexis 4

0.0 (0 reviews)

Sidexis 4 is a comprehensive dental imaging software that centralizes your X-ray diagnostics, 3D scans, and intraoral images into a unified, high-performance workstation for efficient clinical workflows.

Starting at --
Free Trial NO FREE TRIAL
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SimplePractice

0.0 (0 reviews)

SimplePractice is an all-in-one practice management software designed for health and wellness professionals to manage scheduling, billing, documentation, and telehealth through a secure, HIPAA-compliant cloud platform.

Starting at $29/mo
Free Trial 30 days

Quick Comparison

Feature Sidexis 4 SimplePractice
Website dentsplysirona.com simplepractice.com
Pricing Model Custom Subscription
Starting Price Custom Pricing $29/month
FREE Trial ✘ No free trial ✓ 30 days free trial
Free Plan ✘ No free plan ✘ No free plan
Product Demo ✓ Request demo here ✓ Request demo here
Deployment desktop cloud mobile
Integrations Sidexis iX SICAT Dentsply Sirona Hub Microsoft Windows DICOM Google Calendar iCal Microsoft Outlook Stripe
Target Users small-business mid-market enterprise solopreneur small-business mid-market
Target Industries healthcare healthcare
Customer Count 0 0
Founded Year 1877 2012
Headquarters Charlotte, USA Santa Monica, USA

Overview

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Sidexis 4

Sidexis 4 serves as the digital heart of your dental practice, bringing all your diagnostic data together in one place. You can view 2D X-rays, 3D volumes, and intraoral camera images side-by-side without switching between different programs. This unified interface helps you spot clinical details faster and explains treatment plans to your patients more effectively using visual evidence.

The software is designed for dental professionals ranging from solo practitioners to large multi-specialty clinics. By integrating directly with your imaging hardware and practice management systems, it eliminates manual data entry and reduces the time you spend on administrative tasks. You can manage the entire patient history on a single timeline, ensuring you never lose track of clinical changes over time.

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SimplePractice

SimplePractice is a dedicated practice management solution built to help you run your health and wellness business more efficiently. Whether you are a solo practitioner or managing a group practice, you can handle every aspect of your workflow—from initial client intake and scheduling to paperless documentation and automated billing—all within a single, secure environment.

You can eliminate manual administrative tasks by using the integrated client portal, which allows your patients to book appointments and complete digital intake forms online. The platform also includes built-in telehealth capabilities, enabling you to conduct secure video sessions without needing third-party apps. It simplifies your financial management with integrated credit card processing and automated insurance claim filing, helping you get paid faster while maintaining full HIPAA compliance.

Overview

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Sidexis 4 Features

  • Integrated Timeline View your patient's entire diagnostic history chronologically to track clinical changes and treatment progress over several years.
  • Compare Function Open multiple 2D and 3D images simultaneously to compare pre-operative and post-operative results on a single screen.
  • Light Box Mode Organize and display various image types in a digital light box to simplify complex diagnostic sessions.
  • 3D/2D Synergy Navigate through 3D volumes while simultaneously viewing 2D slices to gain a complete anatomical perspective.
  • Communication Tools Use built-in drawing and measurement tools to highlight findings and explain treatment options clearly to your patients.
  • DICOM Compliance Export and import patient data easily using international standards to collaborate with external labs and specialists.
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SimplePractice Features

  • Paperless Intake. Send digital intake forms and legal documents to your clients so they can sign them electronically before their first visit.
  • HIPAA-Compliant Telehealth. Conduct secure high-definition video appointments directly through the platform on your computer or mobile device with no extra software.
  • Online Appointment Booking. Give your clients the freedom to request appointments online through a professional portal that syncs instantly with your calendar.
  • Automated Billing. Generate invoices, process credit card payments, and send automated billing reminders to your clients to ensure you get paid on time.
  • Insurance Claim Filing. Submit primary insurance claims electronically in just a few clicks and track their status directly within your dashboard.
  • Mobile Clinician App. Manage your schedule, view client records, and finish your progress notes from anywhere using the dedicated mobile app.

Pricing Comparison

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Sidexis 4 Pricing

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SimplePractice Pricing

Starter
$29
  • Unlimited clients
  • Paperless intake forms
  • Client Portal
  • Mobile app access
  • HIPAA-compliant storage
  • Integrated credit card processing

Pros & Cons

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Sidexis 4

Pros

  • Seamless integration with Sirona 2D and 3D imaging hardware
  • Intuitive timeline view simplifies tracking patient history over time
  • High-quality 3D rendering provides excellent diagnostic clarity
  • Modern user interface is much cleaner than older versions

Cons

  • Requires high-performance hardware for smooth 3D rendering
  • Learning curve when transitioning from older imaging platforms
  • Pricing is not transparent and requires dealer contact
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SimplePractice

Pros

  • Intuitive interface makes it easy to learn quickly
  • Excellent mobile app for managing tasks on the go
  • Streamlined insurance filing saves hours of manual work
  • Professional client portal improves the patient experience
  • Reliable HIPAA-compliant video quality for telehealth sessions

Cons

  • Customer support is primarily chat and email based
  • Pricing has increased significantly for long-term users
  • Limited customization options for specific medical specialties
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